Kurt Cobain's Smells Like Teen Spirit guitar in auction featuring The Beatles, Prince and Elton John

A still from a video clip of Kurt Cobain playing guitar

With four power chords, Kurt Cobain's Fender guitar took teenage angst mainstream.  (Supplied: Nirvana)

In short:

The guitar played by Nirvana front man Kurt Cobain in the Smells Like Teen Spirit video is being auctioned by Christies in a treasure trove of pop culture items.

The left-handed 1969 Fender Competition Mustang has an estimated sale price of up to $7.14 million ($US5 million).

Also for sale are The Beatles drummer Ringo Starr's drum kit, guitars played by Johnny Cash, David Gilmour and Eric Clapton, and a saddle worn by champion US racehorse Secretariat.